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Toxicant and Disease Database

The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. See a full description of the database and its limitations.

See also CHE's compilation of other Databases and Resources

For questions or comments about the database, please contact Nancy Hepp through our Contact form.

Thyroid disorders - hypothyroidism

Causes    Grouped by strength of evidence

Strong Evidence

cobalt

ionizing radiation

PBBs

PCBs (polychlorinated biphenyls), not otherwise specified

phenols

radioactive iodine (I131)

thiocyanate

Good Evidence

1,1-dichloroethane

dioxins / TCDD

ethylene thiourea (ETU)

perchlorate

Limited Evidence

carbamates

carbon disulfide

fluoride

fungicides

hexachlorobenzene

lead

maneb

mercury

organochlorine pesticides

organophosphates

PBDEs (polybrominated diphenyl ethers), not otherwise specified

pentachlorophenol (PCP)

pesticides

zineb

Notes