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Toxicant and Disease Database

The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. See a full description of the database and its limitations.

See also CHE's compilation of other Databases and Resources

For questions or comments about the database, please contact Nancy Hepp through our Contact form.

Cranio-facial malformations*

Causes    Grouped by strength of evidence

Strong Evidence

ethyl alcohol (ethanol)

toluene

Good Evidence

ethylene glycol ethers

ionizing radiation

mercury

PCBs (polychlorinated biphenyls), not otherwise specified

solvents

Limited Evidence

cadmium

carbon disulfide

cyanazine

lead

methylazoxymethanol acetate

organophosphate pesticides

tetrachloroethylene (PCE)

Notes

*Includes microcephaly, macrocephaly, gingival hyperplasia, wide saggital suture, facial edema, and exophthalmos.