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Toxicant and Disease Database

The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. See a full description of the database and its limitations.

See also CHE's compilation of other Databases and Resources

For questions or comments about the database, please contact Nancy Hepp through our Contact form.

Congenital malformations - general

Causes    Grouped by strength of evidence

Strong Evidence

anesthetic gases

ethyl alcohol (ethanol)

ionizing radiation

Good Evidence

Agent Orange

arsenic

carbon monoxide

ethylene glycol ethers

mercury

solvents

tobacco smoke

Limited Evidence

bisphenol A

carbaryl

carbon disulfide

chromic acid

ethylene oxide

metam sodium

methyl bromide

pentachlorophenol (PCP)

pesticides

vinyl chloride

Notes

In addition to individual pesticides that have been identified in some epidemiological studies, maternal pesticide exposure in the home or occupationally (farmers, agricultural workers) has been associated with birth defects. The design of the majority of these studies were not able to identify specific pesticides associated with birth defects .