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Toxicant and Disease Database

The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. See a full description of the database and its limitations.

See also CHE's compilation of other Databases and Resources

For questions or comments about the database, please contact Nancy Hepp through our Contact form.

Reduced fertility - female (infertility and subfertility)

Causes    Grouped by strength of evidence

Strong Evidence

anesthetic gases

estrogens / DES

ionizing radiation

tobacco smoke (active smoking)

Good Evidence

1-bromopropane

2-bromopropane

ethylene glycol ethers

formaldehyde

lead

nitrous oxide

pesticides

solvents

tetrachloroethylene (PCE)

tobacco smoke (secondhand)

toluene

Limited Evidence

chlordecone

DDT/DDE

dioxins / TCDD

herbicides

hexachlorobenzene

mercury

organochlorine pesticides

PCBs (polychlorinated biphenyls), not otherwise specified

pentachlorophenol (PCP)

pesticides

styrene

vanadium

Notes

Women exposed to DDT in the womb have been shown to have reduced fertility (increased time to pregnancy) as adults.