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Toxicant and Disease Database

The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. See a full description of the database and its limitations.

See also CHE's compilation of other Databases and Resources

For questions or comments about the database, please contact Nancy Hepp through our Contact form.

Testicular cancer

Causes    Grouped by strength of evidence

Good Evidence

chlordimeform/4-COT

estrogens / DES

pesticides

Limited Evidence

2,4-D

acrylamide

cadmium

chlordane

chlorophenols

dibromochloropropane (DBCP)

dimethylformamide

electromagnetic fields

ethylene glycol ethers

fungicides

herbicides

hexachlorobenzene

hexaconazole

iprodione

linuron

MCPA

methoxychlor

methyl bromide

MTBE

organochlorine pesticides

organophosphates

PCBs (polychlorinated biphenyls), not otherwise specified

pesticides

pronamide

trichloroethylene (TCE)

zinc

Notes

^ - Group 2B human carcinogen (IARC), *4-COT is the metabolite of chlordimeform. Pesticide exposure in applicators, manufacturers, farmers and other occupations with diverse exposures to mixtures of pesticides has been associated with testicular ca. In these studies, it was not possible to correlate an individual pesticide exposure with disease. Parental exposure to pesticides has also been associated with testicular ca. in male offspring.