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Toxicant and Disease Database

The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. See a full description of the database and its limitations.

See also CHE's compilation of other Databases and Resources

For questions or comments about the database, please contact Nancy Hepp through our Contact form.

Hepatocellular cancer (liver cancer)

Causes    Grouped by strength of evidence

Strong Evidence

aflatoxin B1 (aflatoxins)

aflatoxins

androgens

ethyl alcohol (ethanol)

hydrocarbons

N-nitrosodimethylamine

vinyl chloride

Good Evidence

arsenic

bromochloroacetic

captafol

diclofop-methyl

mepanipyrim

PCBs (polychlorinated biphenyls), not otherwise specified

propoxur

resmethrin

thorium dioxide (Thorostat)

trichloroethylene (TCE)

Limited Evidence

1,4-dioxane

2,2',3,3',4,4',5,5',6,6'-decabromodiphenyl ether (BDE-209)

acephate

acifluorfen

aldrin

amitrole

benomyl

benzene

bromacil

bromoxynil

carbon tetrachloride

chloramben

chlorbenzilate

chlordane

chlordimeform/4-COT

chloroform

cyproconazole

DDT/DDE

dibromochloropropane (DBCP)

dichlobenil

dichloropropene

dicofol

dinitrotoluenes

endrin

ethylene thiourea (ETU)

formalin

fungicides

furancarboxamide

furans, not otherwise specified

furmecyclox

halogenated hydrocarbons

haloxyfop-methyl

heptachlor

herbicides

hexachlorobenzene

hydrazines

iprodione

isoprene

lactofen

lindane

metam sodium

methylene chloride

metolachlor

mirex

MTBE

nitrobenzene

nitrofen

nitrosamines

organochlorine pesticides

organophosphates

oxadiazon

oxadixyl

oxyfluorofen

p-dichlorobenzene

PBBs

pentachlorophenol (PCP)

permethrin

pesticides

phenoxyacetic herbicides

prochloraz

pronamide

propiconazole

quizalofop-ethyl

solvents

TCDD

tebuconazole

tetrachloroethylene (PCE)

tetrachlorovinphos

tetrafluoroethylene

tobacco smoke (active smoking)

toxaphene

triadimefon

triadimenol

triallate

uniconazole

vinyl bromide

vinyl fluoride

Notes

+ - Group 1 human carcinogen (IARC), # - Group 2A human carcinogen (IARC), ^ - Group 2B human carcinogen (IARC). Note: many chemicals cause liver cancer in laboratory animals and the list here is incomplete. The links to propoxur, to mepanipyrim and to 2,2',3,3',4,4',5,5',6,6'-decabromodiphenyl ether (BDE-209) are based on animal studies.