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Toxicant and Disease Database

The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. See a full description of the database and its limitations.

See also CHE's compilation of other Databases and Resources

For questions or comments about the database, please contact Nancy Hepp through our Contact form.

COPD (chronic obstructive pulmonary disease)

Causes    Grouped by strength of evidence

Strong Evidence

cement dust

coal dust

cotton dust

particulate air pollution (soot)

tobacco smoke (active smoking)

vanadium

wood dust

Good Evidence

antimony

cadmium

chromium

grain dust

irritant gases

metal fumes

ozone

silica

sodium hydroxide

tobacco smoke (secondhand)

Limited Evidence

ammonia

arsenic

chlorine

manganese

nickel carbonyl

nitrogen dioxide

sulfur dioxide

Notes

Cement dust, chlorine, coal dust, grain dust, cotton/hemp/flax dust, and sulfur dioxide have all been shown to act additively or multiplicatively with tobacco smoke to cause disease.