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Toxicant and Disease Database

The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. See a full description of the database and its limitations.

See also CHE's compilation of other Databases and Resources

For questions or comments about the database, please contact Nancy Hepp through our Contact form.

Coronary artery disease, peripheral vascular disease, atherosclerosis

Causes    Grouped by strength of evidence

Strong Evidence

carbon disulfide

lead

particulate air pollution (soot)

tobacco smoke (active smoking)

tobacco smoke (secondhand)

Good Evidence

arsenic

cadmium

carbon monoxide

dinitrotoluenes

dioxins / TCDD

mercury

TNT (trinitrotoluene)

Limited Evidence

allylamine

aluminum

antimony

B-aminopropionitrile

nitrates / nitrites

PAHs

tungsten carbide

Notes

Organic nitrates exposure (mainly in the explosives industry) includes ammonium, sodium nitrate, ethylene glycol dinitrate, nitroglycerin, and TNT and can cause cardiotoxicity in the absence of heart disease.