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Toxicant and Disease Database

The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. See a full description of the database and its limitations.

See also CHE's compilation of other Databases and Resources

For questions or comments about the database, please contact Nancy Hepp through our Contact form.

carbamates

Diseases linked to this toxicant    Grouped by strength of evidence

Strong Evidence

Arrhythmias

Peripheral neuropathy

Good Evidence

Asthma - irritant

Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span) / mental retardation / developmental delay

Immune suppression

Lymphoma (non-Hodgkin's)

Limited Evidence

Adult-onset leukemias

Autoimmune antibodies (positive ANA, anti-DNA, RF, etc.)

Bladder cancer

Decreased vision (includes blindness, retinopathy, optic neuropathy)

Leukoderma (hypopigmentation)

Lung cancer

Thyroid disorders - hypothyroidism

References

Alexander FE, Patheal SL et al. Transplacental chemical exposure and risk of infant leukemia with MLL gene fusion. Cancer Research. 2001; 61:2542-2546.

Garry VF, Harkins ME, Erickson LL, Long-Simpson LK, Holland SE, Burroughs BL. Birth defects, season of conception, and sex of children born to pesticide applicators living in the Red River Valley of Minnesota, USA. Environmental Health Perspectives. 2002

International Agency for Research on Cancer (IARC). Agents Classified by the IARC Monographs. Accessed in 2010.

Kamel F, Boyes WK, Gladen BC, Rowland AS, Alavanja MC, Blair A, Sandler DP. Retinal degeneration in licensed pesticide applicators. American Journal of Industrial Medicine. 2000 Jun;37(6):618-628.

Klaassen CD, Ed. Casarett and Doull's Toxicology: The Basic Science of Poisons, 6th Edition. New York: McGraw-Hill 2001.

LaDou J, Ed. Occupational and Environmental Medicine, 3rd Edition. New York: Lange Medical/McGraw-Hill Company, 2004.

Leikin JB, Davis A, Klodd DA, Thunder T, Kelafant GA, Paquette DL, Rothe MJ, Rubin R. Selected topics related to occupational exposures. Part V. Occupational cardiovascular disease. Disease-a-Month. 2000 Apr;46(4):311-322.

Rom WM. Environmental and Occupational Medicine, 3rd Edition. Philadelphia: Lippincott Williams & Wilkins Publishers, 1998.

NOTE: Not all the references are currently available, but they will be added as soon as possible. If you need a reference and are unable to find it, please contact us through our contact form