Toxicant and Disease Database

The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. See a full description of the database and our methodology.

See also our compilation of other Databases and Resources

For questions or comments about the database, please contact us through our Contact form.

diesel exhaust

Diseases linked to this toxicant    Grouped by strength of evidence

Strong Evidence

Asthma - irritant

Lung cancer

Rhinitis - irritant

Good Evidence

Asthma - allergen, sensitizer

Myelodysplastic syndrome (pre-leukemia)

Rhinitis - allergic

Limited Evidence

Bladder cancer

Immune suppression

Ovarian cancer


Prostate cancer


Amercian Academy of Pediatrics, Committee on Environmental Health. Ambient air pollution: health hazards to children. Pediatrics. 2004; 114(6):1699-1707.

Cohen SM, Shirai T, Steineck G. Epidemiology and etiology of premalignant and malignant urothelial changes. Scandinavian Journal of Urology and Nephrology. Supplementum. 2000; 205:105-115.

Klaassen CD, Ed. Casarett and Doull's Toxicology: The Basic Science of Poisons, 6th Edition. New York: McGraw-Hill 2001.

LaDou J, Ed. Occupational and Environmental Medicine, 3rd Edition. New York: Lange Medical/McGraw-Hill Company, 2004.

Rom WM. Environmental and Occupational Medicine, 3rd Edition. Philadelphia: Lippincott Williams & Wilkins Publishers, 1998.

NOTE: Not all the references are currently available, but they will be added as soon as possible. If you need a reference and are unable to find it, please contact us through our contact form