Toxicant and Disease Database
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The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. See a full description of the database and our methodology.
See also our compilation of other Databases and Resources
For questions or comments about the database, please contact us through our Contact form.
ethyl alcohol (ethanol)
CAS number: 64-17-5
Diseases linked to this toxicant Grouped by strength of evidence
NOTE: The toxicant–disease relationships shown above were last updated in 2011. The relationships shown here are still valid, but additional research has been conducted since that time. Additional research on this toxicant can be found at this link:
COMPARATIVE TOXICOGENOMICS DATABASE: CURATED RESULTS
This link will direct your search to an external database, the Comparative Toxicogenomics Database (CTD). This database is different from, and complementary to, our database.
More information about sources and methods
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CHE’s Toxicant and Disease Database evaluates existing evidence and categorizes that evidence based on its strength. It is constructed using expert judgment and epidemiological causal inference.
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The CTD, in contrast, is a continually updated resource that presents information on a broad range of literature on chemical-disease relationships. It also provides data on genes, biological processes, and phenotypes related to chemicals and diseases. It does not categorize information based on strength of evidence, include an expert judgment process, or draw causal conclusions about toxicant-disease relationships.
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The link we have provided on this page goes directly to CTD's curated results, which are a subset of the information available through CTD. Curated results in CTD are those for which studies are available on the toxicant-disease relationship.
References for our 2011 disease list
Carpenter DO, Arcaro K, Spink DC. Understanding the human health effects of chemical mixtures. Environmental Health Perspectives. 2002;110(suppl 1):25-42.
Cordero JF. Effect of environmental agents on pregnancy outcomes: disturbances of prenatal growth and development. Medical Clinics of North America. 1990;74(2):279-290.
Damgaard IN, Jensen TK, Petersen JH, Skakkebaek NE, Toppari J, Main KM. Cryptorchidism and maternal alcohol consumption during pregnancy. Environmental Health Perspectives. 2007 Feb;115(2):272-7.
DeBruin LS, Josephy PD. Perspectives on the chemical etiology of breast cancer. Environmental Health Perspectives. 2002 Feb;110 Suppl 1:119-28.
Greenlee AR, Arbuckle TE, Chyou PH. Risk factors for female infertility in an agricultural region. Epidemiology. 2003; 14(4):429-436.
Hruska KS, Furth PA, Seifer DB, Sharara FI, Flaws JA. Environmental factors in infertility. Clinical Obstetrics and Gynecology. 2000 Dec;43(4):821-9.
Klaassen CD, Ed. Casarett and Doull's Toxicology: The Basic Science of Poisons, 6th Edition. New York: McGraw-Hill 2001.
Kukull WA, Larson EB et al. Solvent exposure as a risk factor for Alzheimer's disease: a case-control study. American Journal of Epidemiology. 1995 Jun 1;141(11):1059-71; discussion 1072-9.
LaDou J, Ed. Occupational and Environmental Medicine, 3rd Edition. New York: Lange Medical/McGraw-Hill Company, 2004.
Landrigan PJ, Garg A. Chronic effects of toxic environmental exposures on children's health. Journal of Toxicology. Clinical Toxicology. 2002;40(4):449-56.
Leikin JB, Davis A et al. Selected topics related to occupational exposures. Part IV. Occupational liver disease. Disease-a-Month. 2000 Apr;46(4):296-310.
Li D. Molecular epidemiology of pancreatic cancer. Cancer Journal. 2001 Jul-Aug;7(4):259-65.
Rom WM. Environmental and Occupational Medicine, 3rd Edition. Philadelphia: Lippincott Williams & Wilkins Publishers, 1998.
