Toxicant and Disease Database

The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. See a full description of the database and our methodology.

See also our compilation of other Databases and Resources

For questions or comments about the database, please contact us through our Contact form.

nitrates / nitrites

Diseases linked to this toxicant    Grouped by strength of evidence

Strong Evidence



Myocardial infarction (heart attack)

Good Evidence

Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span) / mental retardation / developmental delay

Raynaud's phenomenon

Stomach cancer

Limited Evidence

Coronary artery disease, peripheral vascular disease, atherosclerosis

Diabetes - Type I

Diabetes - Type I


Klaassen CD, Ed. Casarett and Doull's Toxicology: The Basic Science of Poisons, 6th Edition. New York: McGraw-Hill 2001.

LaDou J, Ed. Occupational and Environmental Medicine, 3rd Edition. New York: Lange Medical/McGraw-Hill Company, 2004.

Longnecker MP, Daniels JL. Environmental contaminants as etiologic factors for diabetes. Environmental Health Perspectives. 2001 Dec;109 Suppl 6:871-6.

Rom WM. Environmental and Occupational Medicine, 3rd Edition. Philadelphia: Lippincott Williams & Wilkins Publishers, 1998.

NOTE: Not all the references are currently available, but they will be added as soon as possible. If you need a reference and are unable to find it, please contact us through our contact form