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CDC, ATSDR

Toxicant and Disease Database

The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. See a full description of the database and our methodology.

See also our compilation of other Databases and Resources

For questions or comments about the database, please contact us through our Contact form.

1,1,1-trichloroethane

CAS number: 71-55-6

Diseases linked to this toxicant    Grouped by strength of evidence

Strong Evidence

Neurobehavioral abnormalities

Steatosis (fatty liver)

Good Evidence

Acute hepatocellular injury (hepatitis)s

Arrhythmias

Autoimmune antibodies (positive ANA, anti-DNA, RF, etc.)

Fetotoxicity (miscarriage / spontaneous abortion, stillbirth)

Scleroderma

Limited Evidence

Cirrhosis

Immune suppression

Multiple myeloma

Peripheral neuropathy

References

Integrated Risk Information System (IRIS). IRIS Assessments. Accessed in 2010.

Klaassen CD, Ed. Casarett and Doull's Toxicology: The Basic Science of Poisons, 6th Edition. New York: McGraw-Hill 2001.

LaDou J, Ed. Occupational and Environmental Medicine, 3rd Edition. New York: Lange Medical/McGraw-Hill Company, 2004.

Lynge E, Anttila A, Hemminki K. Organic solvents and cancer. Cancer Causes and Control. 1997 May;8(3):406-19.

Rom WM. Environmental and Occupational Medicine, 3rd Edition. Philadelphia: Lippincott Williams & Wilkins Publishers, 1998.

NOTE: Not all the references are currently available, but they will be added as soon as possible. If you need a reference and are unable to find it, please contact us through our contact form