[X] CLOSEMAIN MENU

[X] CLOSEIN THIS SECTION

Toxicant and Disease Database

The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. See a full description of the database and its limitations.

See also CHE's compilation of other Databases and Resources

For questions or comments about the database, please contact Nancy Hepp through our Contact form.

pentachlorophenol (PCP)

CAS number: 87-86-5

Diseases linked to this toxicant    Grouped by strength of evidence

Strong Evidence

Acute tubular necrosis

Good Evidence

Aplastic anemia

Chloracne

Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span) / mental retardation / developmental delay

Immune suppression

Low birth weight / small for gestational age / intra-uterine growth retardation

Pancreatic cancer

Renal (kidney) cancer

Limited Evidence

Adrenal cancer

Angiosarcoma (hepatic)

Autoimmune antibodies (positive ANA, anti-DNA, RF, etc.)

Brain cancer - adult

Congenital malformations - general

Delayed growth

Fetotoxicity (miscarriage / spontaneous abortion, stillbirth)

Hepatocellular cancer (liver cancer)

Lymphoma (non-Hodgkin's)

Nasopharyngeal / sino-nasal cancer

Pancreatitis

Reduced fertility - female (infertility and subfertility)

Thrombocytopenic purpura

Thyroid disorders - hypothyroidism

References

Hruska KS, Furth PA, Seifer DB, Sharara FI, Flaws JA. Environmental factors in infertility. Clinical Obstetrics and Gynecology. 2000 Dec;43(4):821-9.

Jorens PG, Schepens PJ. Human pentachlorophenol poisoning. Human & Experimental Toxicology. 1993 Nov;12(6):479-495.

Khurana V, Barkin JS. Pancreatitis induced by environmental toxins. Pancreas. 2001 Jan; 22(1):102-104.

Klaassen CD, Ed. Casarett and Doull's Toxicology: The Basic Science of Poisons, 6th Edition. New York: McGraw-Hill 2001.

LaDou J, Ed. Occupational and Environmental Medicine, 3rd Edition. New York: Lange Medical/McGraw-Hill Company, 2004.

Rom WM. Environmental and Occupational Medicine, 3rd Edition. Philadelphia: Lippincott Williams & Wilkins Publishers, 1998.

NOTE: Not all the references are currently available, but they will be added as soon as possible. If you need a reference and are unable to find it, please contact us through our contact form