Toxicant and Disease Database
The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. See a full description of the database and its limitations.
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Diseases linked to this toxicant Grouped by strength of evidence
Aschengrau A, Rogers S, Ozonoff D. Perchloroethylene-contaminated drinking water and the risk of breast cancer: additional results from Cape Cod, Massachusetts, USA. Environmental Health Perspectives. 2003 Feb;111(2):167-73.
Brautbar N. Industrial solvents and kidney disease. International Journal of Occupational and Environmental Health. 2004 Jan-Mar;10(1):79-83.
Buzio L, Tondel M, De Palma G, Buzio C, Franchini I, Mutti A, Axelson O. Occupational risk factors for renal cell cancer: an Italian case-control study. Medicina del Lavoro. 2002 Jul-Aug; 93(4):303-9.
Caress S, Steinemann A. A review of a two-phase population study of multiple chemical sensitivities. Environmental Health Perspectives. 2003; 111(12):1490-1497.
Carpenter DO, Arcaro K, Spink DC. Understanding the human health effects of chemical mixtures. Environmental Health Perspectives. 2002;110(suppl 1):25-42.
Colt JS, Blair A. Parental occupational exposures and risk of childhood cancer. Environmental Health Perspectives. 1998;106(Suppl 3):909-925.
Cooper GS, Miller FW, Germolec DR. Occupational exposures and autoimmune diseases. International Immunopharmacology. 2002;2:303-313.
D'Cruz D. Autoimmune diseases associated with drugs, chemicals and environmental factors. Toxicology Letters. 2000 Mar 15;112-113:421-32.
Eskenazi B, Bracken MB, Holford TR, Grady J. Exposure to organic solvents and hypertensive disorders of pregnancy. American Journal of Industrial Medicine. 1988; 14(2):177-88.
Figà-Talamanca I, Traina ME, Urbani E. Occupational exposures to metals, solvents, and pesticides: recent evidence on male reproductive effects and biological markers. Occupational Medicine (Oxford, England). 2001 May;51(3):174-88.
Freed DM, Kandel E. Long-term exposure and the diagnosis of dementia. NeuroToxicology. 1988 Fall;9(3):391-400.
Hardell L, Lindström G, van Bavel B, Fredrikson M, Liljegren G. Some aspects of the etiology of non-Hodgkin's lymphoma. Environmental Health Perspectives. 1998 Apr;106(Suppl 2):679-681.
Hay A, Singer CRJ. Wood preservatives, solvents, and thrombocytopenic purpura. Lancet. 1991 Sep 21;338(8769):766.
Hruska KS, Furth PA, Seifer DB, Sharara FI, Flaws JA. Environmental factors in infertility. Clinical Obstetrics and Gynecology. 2000 Dec;43(4):821-9.
Kaerlev L, Teglbjaerg PS et al. Occupational risk factors for small bowel carcinoid tumor: a European population-based case-control study. Journal of Occupational and Environmental Medicine. 2002 Jun;44(6):516-22.
Kauppinen T, Partanen T, Degerth R, Ojajärvi A. Pancreatic cancer and occupational exposures. Epidemiology. 1995 Sep;6(5):498-502.
Khattak S, K-Moghtader G, McMartin K, Barrera M, Kennedy D, Koren G. Pregnancy outcome following gestational exposure to organic solvents: a prospective controlled study. Journal of the American Medical Association. 1999 Mar 24-31;281(12):1106-9.
Klaassen CD, Ed. Casarett and Doull's Toxicology: The Basic Science of Poisons, 6th Edition. New York: McGraw-Hill 2001.
Kukull WA, Larson EB et al. Solvent exposure as a risk factor for Alzheimer's disease: a case-control study. American Journal of Epidemiology. 1995 Jun 1;141(11):1059-71; discussion 1072-9.
LaDou J, Ed. Occupational and Environmental Medicine, 3rd Edition. New York: Lange Medical/McGraw-Hill Company, 2004.
Landrigan PJ, Garg A. Chronic effects of toxic environmental exposures on children's health. Journal of Toxicology. Clinical Toxicology. 2002;40(4):449-56.
Landtblom AM, Flodin U, Söderfeldt B, Wolfson C, Axelson O. Organic solvents and multiple sclerosis: a synthesis of current evidence. Epidemiology 1996;7(4):429-33.
Lane SE, Watts RA, Bentham G, Innes NJ, Scott DG. Are environmental factors important in primary systemic vasculitis? A case-control study. Arthritis and Rheumatism. 2003 Mar;48(3):814-23.
Leikin JB, Davis A et al. Selected topics related to occupational exposures. Part IV. Occupational liver disease. Disease-a-Month. 2000 Apr;46(4):296-310.
Leikin JB, Davis A, Klodd DA, Thunder T, Kelafant GA, Paquette DL, Rothe MJ, Rubin R. Selected topics related to occupational exposures. Part V. Occupational cardiovascular disease. Disease-a-Month. 2000 Apr;46(4):311-322.
Loffredo CA. Epidemiology of cardiovascular malformations: prevalence and risk factors. American Journal of Medical Genetics. 2000 Winter;97(4):319-25.
Maves MD. Epidemiologic studies of environmental agents and systemic autoimmune diseases. Environmental Health Perspectives. 1999 Oct;107 Suppl 5:743-8.
Rom WM. Environmental and Occupational Medicine, 3rd Edition. Philadelphia: Lippincott Williams & Wilkins Publishers, 1998.
NOTE: Not all the references are currently available, but they will be added as soon as possible. If you need a reference and are unable to find it, please contact us through our contact form