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Toxicant and Disease Database

The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. See a full description of the database and its limitations.

See also CHE's compilation of other Databases and Resources

For questions or comments about the database, please contact Nancy Hepp through our Contact form.

metals

Diseases linked to this toxicant    Grouped by strength of evidence

Strong Evidence

Acute tubular necrosis

Bronchitis - chronic

Contact dermatitis - allergic

Contact dermatitis - irritant

Hearing loss

Olfactory alterations (hyposmia, anosmia, dysomias)

Good Evidence

Pneumoconiosis

Limited Evidence

Mycosis fungoides (cutaneous T-cell lymphoma)

Myelodysplastic syndrome (pre-leukemia)

References

Colt JS, Blair A. Parental occupational exposures and risk of childhood cancer. Environmental Health Perspectives. 1998;106(Suppl 3):909-925.

Freed DM, Kandel E. Long-term exposure and the diagnosis of dementia. NeuroToxicology. 1988 Fall;9(3):391-400.

Klaassen CD, Ed. Casarett and Doull's Toxicology: The Basic Science of Poisons, 6th Edition. New York: McGraw-Hill 2001.

LaDou J, Ed. Occupational and Environmental Medicine, 3rd Edition. New York: Lange Medical/McGraw-Hill Company, 2004.

Rom WM. Environmental and Occupational Medicine, 3rd Edition. Philadelphia: Lippincott Williams & Wilkins Publishers, 1998.

NOTE: Not all the references are currently available, but they will be added as soon as possible. If you need a reference and are unable to find it, please contact us through our contact form