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Toxicant and Disease Database

The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. See a full description of the database and its limitations.

See also CHE's compilation of other Databases and Resources

For questions or comments about the database, please contact Nancy Hepp through our Contact form.

Colorectal cancer

Causes    Grouped by strength of evidence

Good Evidence

1,1-dichloroethane

alachlor

aromatic amines

chlorination byproducts

ionizing radiation

solvents

Limited Evidence

2,4-D

2,4,5-T

acrylonitrile

aldrin / dieldrin

asbestos

chlorophenols

chlorpyrifos

DDT/DDE

dioxins / TCDD

nitrosamines

organochlorine pesticides

organophosphates

PAHs

PCBs (polychlorinated biphenyls), not otherwise specified

pesticides

phenoxyacetic herbicides

PhIP (2-amino-1-methyl-6-phenylimidazol(4,5-b)pyridine)

toluene

xylene

Notes

Organic solvent exposure in commercial pressmen has been associated with colo-rectal cancer. Limited data showing association of colo-rectal ca in children with insecticide use. In addition to groups or individual pesticides listed, pesticide exposure in applicators, manufacturers and agricultural workers has been associated with colorectal ca. In these situations, the individual is exposed to mixtures of pesticides or different pesticides at different times and a correlation between an individual pesticide and disease can not be made.