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The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. In 2025, we have also added links to information available in the Comparative Toxicogenomics Database (CTD). See a full description of the database and our methodology.
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Altered sex ratio
Causes Grouped by strength of evidence
Good Evidence | Limited Evidence |
Notes
In families where fungicides were applied by the father, significantly fewer male children were born. An increase in male fetal death has been observed due to methyl mercury in Minamata, Japan in the 1950s. For one sample reference on altered sex ratio, see: James WH. 1995. Offspring sex ratio as an indicator of reproductive hazards associated with pesticides. Occupational & Environmental Medicine 52(6):429–430. For additional information on altered sex ratio, PubMed can be searched using the MeSH ID D012744.