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Toxicant and Disease Database

The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. See a full description of the database and its limitations.

See also CHE's compilation of other Databases and Resources

For questions or comments about the database, please contact Nancy Hepp through our Contact form.

Prostate cancer

Causes    Grouped by strength of evidence

Good Evidence

Agent Orange

aromatic amines

methyl bromide

organochlorine pesticides

PAHs

pesticides

solvents

Limited Evidence

acrylonitrile

androgens

atrazine

bisphenol A

cadmium

chlorophenols

chromium

DDT/DDE

dibromochloropropane (DBCP)

dichlorvos

diesel exhaust

estrogens / DES

methylene chloride

nickel

PCBs (polychlorinated biphenyls), not otherwise specified

pesticides

phenoxyacetic herbicides

PhIP (2-amino-1-methyl-6-phenylimidazol(4,5-b)pyridine)

trichloroethylene (TCE)

Notes

# - Group 2A human carcinogen, ^ - Group 2B human carcinogen (IARC) (IARC), Polymorphisms of genes for enzymes NAT-1, CYP2D6*B, and GSTT1 have been weakly associated with increased risks of prostate ca. Pesticide exposure in applicators, manufacturers, and farmers has been associated with prostate ca. In these studies, the individual was exposed to mixtures of pesticides that are unidentifiable from study designs.