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CHE Toxicant and Disease Database

Multiple myeloma

Causes [strength of evidence]:

Notes
Organic solvent exposure in painters has been associated with multiple myeloma. In addition to the pesticides listed, unspecified pesticide exposure in applicators, manufacturers, and agricultural workers has been associated with multiple myeloma. In these situations, the individual is exposed to mixtures of pesticides or different pesticides at different times. Associations between a specific pesticide exposure and disease can not be made.

References:
  • Baker SR and Wilkinson CF, ed. The Effects of Pesticides on Human Health. Workshop Proceedings, Advances in Modern Environmental Toxicology XVIII. May 9-11, 1998. Princeton Science Publishing, Princeton.
  • Becker N. et al. Asbestos Exposure and Malignant Lymphomas - a Review of the Epidemiological Literature. 2001;74:459-469.
  • Bertazzi, P.A. et al. Health Effects of dioxin exposure: a 20-year mortality study. Am J Epidemiol 2001;153(11):1031-1044.
  • Cocco, P. et al Cancer Mortality and environmental Exposure to DDE in the United States. Environ Health Perspect 2000;108(1):1-4.
  • Dich, J. et al. Pesticides and Cancer. Cancer Causes and Control 1997;8:420-443.
  • Frumkin, H. Agent Orange and Cancer: an Overview for Clinicians. CA Cancer J Clin 2003;53(4):245-255.
  • International Agency for Research on Cancer (IARC)
  • Lynge, E. et al. Organic Solvents and Cancer. Cancer Causes and Control 1997;8:406-419.
  • Solomon G. et al. Pesticides and Human Health: A Resource for Health Professionals. A peer-reviewed report by Physicians for Social Responsibility (LA and Greater Bay Area chapters) and Californians for Pesticide Reform. 2000. Available on-line at: http:

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