CHE Toxicant and Disease Database
Displaying diseases linked to lead (grouped by strength of evidence).
Strong:
- Abnormal sperm (morphology, motility, and sperm count)
- Acute tubular necrosis
- ADD/ADHD, hyperactivity
- Anemia (including hemolytic)
- Behavioral problems*
- Cataracts
- Chronic renal disease
- Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span) / mental retardation / developmental delay
- Coronary artery disease, peripheral vascular disease, atherosclerosis
- Decreased coordination / dysequilibrium*
- Gout
- Hearing loss
- Hypertension (high blood pressure)
- Peripheral neuropathy
- Psychiatric disturbances (disorientation, hallucinations, psychosis, delirium, paranoias, anxiety/depression, emotional lability, mood changes, euphoria)
- Reduced fertility - male (infertility and subfertility)
- Seizures
Good:
- Altered time to sexual maturation (accelerated or delayed puberty)
- Arrhythmias
- Cardiomyopathy
- Cerebrovascular disease (stroke)
- Delayed growth
- Fetotoxicity (miscarriage / spontaneous abortion, stillbirth)
- Glomerulonephritis
- Hormonal changes (levels of circulating sex hormones - FSH/LH, Inhibin, and/or estrogens, progesterones, androgens, prolactin)
- Immune suppression*
- Low birth weight / small for gestational age / intra-uterine growth retardation
- Menstrual disorders (abnormal bleeding, short cycles, long cycles, irregular cycles, painful periods)
- Myocardial infarction (heart attack)
- Nephrotic syndrome
- Porphyria (toxic)
- Preterm delivery
- Reduced fertility - female (infertility and subfertility)
Limited:
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