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last updated in 2004 

Ahlbom J, Fredriksson A, Eriksson P. 1995. Exposure to an organophosphate (DFP) during a defined period in neonatal life indusces permanent changes in brain muscarinic receptors and behaviour in adult mice. Brain Res 677:13-19.

Amin-Zaki L, Ehassani S, Majeed MA, Clarkson T, Doherty R, Greenwood M, Giovanoli-Jakubezak T. 1976. Perinatal methylmercury poisoning in Iraq. Am J Dis Child 130:1070-1076.

Atchison WD, Hare MF. 1994. Mechanisms of methylmercury-induced neurotoxicity. FASEB J 8(9):622-629.

Baumgaertel A, Copeland L, Wolwraich M. 1996. Attention deficit hyperactivity disorder. In: Disorders of Development and Learning, 2nd ed (Wolraich M, ed). St. Louis, MO:Mosby.

Birnbaum, LS and DF Staskal. 2004. Brominated flame retardants: cause for concern? Environmental Health Perspectives 112: 9-17.

Boyes WK, Miller DB. 1998. A review of rodent models of manganese neurotoxicity. NeuroToxicology 19(3):468.

Boyle C, Decouffle P, Yeargin-Allsopp M. 1994. Prevalence and health impact of developmental disabilities in US children. Pediatrics 93(3):399-403.

Brouwer A, Longnecker M, Birnbaum L, Cogliano J, Kostyniak P, Moore J, Schantz S, Winneke G. 1999. Characterization of potential endocrine-related health effects at low-dose levels of exposure to PCBs. Environmental Health Perspectives 107(suppl 4):639-648.

Byrd, RS, 2002. The Epidemiology of Autism in California: A Comprehensive Pilot Study. Report to the Legislature on the Principal Findings.

California Department of Developmental Services. 1999. Changes in the Population of Persons with Autism and Pervasive Developmental Disorders in California’s Developmental Services System: 1987 through 1998. A Report to the Legislature March 1, 1999. Sacramento CA: California Health and Human Services Agency. http://www.dds.cahwnet.gov/Autism/main/incidencrptfinal.pdf (cited 26 October 2001).

Canfield, RL, CR Henderson, DA Cory-Slectha, C Cox, TA Jusko and BP Lanphear. 2003. Intellectual impairment in children with blood lead concentrations below 10 µg per deciliter. New England Journal of Medicine 348:1517-1526.

Castellanos, FX, PP Lee, W Sharp, NO Jeffries, DK Greenstein, LS Clasen, JD Blumenthal, RS James, CL Ebens, JM Walter, A Zijdenbos, AC Evans, JN Giedd and JL Rapoport. 2002. Developmental trajectories of brain volume abnormalities in children and adolescents with attention-deficit/hyperactivity disorder. JAMA 288:1740-1748.

Centers for Disease Control and Prevention. Dept of Health and Human Services. 2001. National Report on Human Exposure to Environmental Chemicals.

Collipp PJ, Chen SY, Maitinsky S. Manganese in infant formulas and learning disability. Ann Nutri Metab 27:488-494.

Costa L, Li W, Richter R, Shih D, Lusis A, Furlong C. 1999. The role of paraoxonase (PON1) in the detoxification of organophosphates and its human polymorphism. Chem-Biol Interact 119-120: 429-438.

Courchesne, E, R Carper and N akshoomoff. 2003. Evidence of brain overgrowth in the first year of life in autism. JAMA 290: 337-344.

Cramer S, Ellis E, eds. Learning Disabilities: Lifelong Issues. Baltimore, MD:Paul H. Brookes Publishing.

Crinella FM, Cordova EJ, Ericson JE. 1998. Manganese, aggression, and attention-deficit hyperactivity disorder. Neurotoxicology 19(3):468-469.

Crump KS, Kjellstrom T, Shipp AM, Silvers A, Stewart A. 1998. Influence of prenatal mercury exposure upon scholastic and psychological test performance: benchmark analysis of a New Zealand cohort. Risk Anal 18(6):701-713.

Curl CL, Fenske RA, Elgethun K. Organophosphorus pesticide exposure of urban and suburban preschool children with organic and conventional diets. Environ Health Perspect. 2003 Oct;111(13):A688-9; author reply A89-91.

Darnerud P, Eriksen G, Johannesson T, Larsen P, Viluksela M. 2001. Polybrominated diphenyl ethers: occurrence, dietary exposure, and toxicity. Environmental Health Perspectives 109(suppl 1):49-68.

Dorfmueller MA, Henne S, York R, et al. 1979. Evaluation of teratogenicity and behavioral toxicity with inhalation exposure of maternal rats to trichloroethylene. Toxicology 14(2):153-166.

Dorner K, Dziadzka S, Hohn A, Sievers E, Oldigs H, Schulz-Lell G, Schaub J. 1989. Longitudinal manganese and copper balances in young infants and preterm infants fed on breast milk and adapted cow's milk formula. Br J Nutr 61(3):559-572.

Eriksson P, Fredriksson A. 1991. Neurotoxic effects of two different pyrethroids, bioallethrin and deltamethrin, on immature and adult mice: changes in behavioural and muscarinic receptor variables. Toxicol Appl Pharmacol 108:78-85.

Eriksson P, Viberg H, Jakobsson E, Orn U, Fredriksson A. 2002. A Brominated Flame Retardant, 2,2',4,4',5-Pentabromodiphenyl Ether: Uptake, Retention, and Induction of Neurobehavioral Alterations in Mice during a Critical Phase of Neonatal Brain Development. Toxicol Sci 67(1):98-103

Eskenazi B, Castorina R. 1999. Association of prenatal maternal or postnatal child environmental tobacco smoke exposure and neurodevelopmental and behavioral problems in children. Environmental Health Perspectives 107:991-1000.

Goldman L, Genel M, Bezman R, Slanetz P. 1998. Diagnosis and treatment of attention deficit hyperactivity disorder in children and adolescents. J Am Med Assoc 279(14):1100-1107.

Gogtay, N, JN Giedd, L Lusk, KM Hayashi, D Greenstein, C Vaituzis, DH Herman, TF Nugent, L Clasen, AW Toga, JL Rapoport and PM Thompson. 2004. Dynamic mapping of human cortical development during childhood through early adulthood. Proceedings of the National Academy of Sciences of the USA 101:8174-8179.

Grandjean P, Weihe P, White R, Debes F, Araki S, Yokohama K, Murata K, Sorensen N, Dahl R. 1997. Cognitive deficit in 7-year-old children with prenatal exposure to methylmercury. Neurotoxicol Teratol 19(6):417-428.

Guillette EA, Meza MM, Aquilar MG, Soto AD, Enedina I. 1998. An anthropological approach to the evaluation of preschool children exposed to pesticides in Mexico. Environmental Health Perspectives 106:347-353.

Haddow JE, Palomaki GE, Allan W, Williams J, Knight G, Gagnon J, O'Heir C, Mitchell M, Hermos R, Waisbren S, et al. 1999. Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child. New England Journal of Medicine 341(8):549-555.

Harada H. Congenital Minamata disease: intrauterine methylmercury poisoning. Teratology 18:285-288.

Hass U, Lund SP, Simonsen L, Fries AS. 1995. Effects of prenatal exposure to xylene on postnatal development and behavior in rats. Neurotoxicol Teratol 17(3):341-349.

Hess, RA and PS Cooke. 1996. Neonatal thyroid status as one determinant of adult testis size. pp 11-14 in Chapin, RE, JT Stevens, CL Hughes, WR Kelce, RA Hess and GP Daston. Symposium Overview. Endocrine modulation of reproduction. Fundamental and Applied Toxicology 29: 1-17.

Hightower JM, Moore D. Mercury levels in high-end consumers of fish. Environ Health Perspect. 2003 Apr;111(4):604-8. 

Hites, RA. 2004. Polybrominated Diphenyl Ethers in the Environment and in People: A Meta-Analysis of Concentrations. Environmental Science and Technology 38: 945 - 956.

Hougaard KS, Hass U, Lund SP, Simonsen L. 1999. Effects of prenatal exposure to toluene on postnatal development and behavior in rats. Neurotoxicol Teratol 21(3):241-250.

International Joint Commission United States and Canada. 1978. Great Lakes Water Quality Agreement, 1972; renewed 1978.

Jacobson JL, Jacobson SW. 1990. Effects of in utero exposure to PCBs and related contaminants on cognitive functioning in young children. J Pediatr 116(1):38-45.

Jacobson JL, Jacobson SW. 1996. Intellectual impairment in children exposed to polychlorinated biphenyls in utero. New England Journal of Medicine 335:783-789.

Jones HE, Balster RL. 1998. Inhalant abuse in pregnancy. Obstet Gynecol Clin North Am 25(1):153-167.

Jones HE, Balster RL. 1997. Neurobehavioral consequences of intermittant prenatal exposure to high concentrations of toluene. Neurotoxicol Teratol 19(4):305-313.

Khanna VK, Husain R, Hanig JP, et al. 1991. Increased neurobehavioral toxicity of styrene in protein malnourished rats. Neurotoxicol Teratol 13:153-159.

Koopman-Esseboom C, Morse D, Weisglas-Kuperus N, Lutkeschipholt I, van der Paauw C, Tuinstra L, Brouwer A, Sauer P. 1994. Effects of dioxins and polychlorinated biphenyls on thyroid hormone status of pregnant women and their infants. Pediatr Res 36:468-473.

Kostas J, Hotchkin J. 1981. Behavioral effects of low-level perinatal exposure to toluene in mice. Neurobehav Toxicol Teratol 3(4):467-469.

Lanphear BP, Dietrich K, Auinger P, Cox C. 2000. Cognitive deficits associated with blood lead concentrations <10 microg/dL in US children and adolescents. Public Health Rep 115(6):521-9.

Lonky E, Reihman J, Darvill T. 1996. Neonatal behavioral assessment scale performance in humans influenced by maternal consumption of environmentally contaminated Lake Ontario fish. J Great Lakes Res 22(2):198-212.

Lonnerdal B. 1994. Nutritional aspects of soy formula. Acta Pediatr Suppl 402:105-108.

Madsen, KM, A Hviid, M Vestergaard, D Schendel, J Wohlfahrt, P Thorsen, J Olsen and M Melbye 2002. A population-based study of measles, mumps and rubella vaccination and autism. New England Journal of Medicine 347:1477-82.

McCarthy S. Threat of NAFTA case kills Canada's MMT ban. The Globe and Mail. p. a1. July 20, 1998.

Meerts T, van Zanden J, Luijks E, van Leeuwen-Bol I, Marsh G, Jakobsson E, Bergman A. 2000. Potent competitive interactions of some brominated flame retardants and related compounds with human transthyretin in vitro. Toxicol Sci 56:95-104.

Meironyté, D.Å Bergman and K Norén, K. 1998. Organohalogen Compounds. Swedish Environmental Protection Agency: Stockholm, Sweden, 1998; Vol. 35

Meironyté D, Norén K, Bergman Å. 1999. Analysis of polybrominated diphenyl ethers in Swedish human milk. A time-related trend study, 1972-1997. J Toxicol Environ Health A 58(6):329-41.

Mena I. 1974. The role of manganese in human disease. Ann Clin Lab Sci 4(6):487-491.

Mirkova E, Zaikov C, Mikhailova A, et al. Prenatal toxicity of xylene. J Hyg Epidemiol Immunol 27(3):337-343.

Moffit. TE. 1993. Adolescence-limited and life-course-persistent antisocial behavior: A developmental taxonomy. Psychological Review 100:674-701.

Myers, GJ, PW Davidson, C Cox, CF Shamlaye, D Palumbo, E Cernichiari, J Sloane-Reeves, GE Wilding, J Kost, L-S Huang, and TW Clarkson. 2003. Prenatal methylmercury exposure from ocean fish consumption in the Seychelles child development study. Lancet 361: 1686-92.

National Information Center for Children and Youth with Disabilities. 2001. Emotional Disturbance. Fact Sheet 5.

National Research Council. 2000. Toxicological Effects of Methylmercury. Washington, DC: National Academy Press.

Needham L, Hill R, Ashley D, Pirkle J, Sampson E. 1995. The priority toxicant reference range study: interim report. Environ Health Perspect 103(suppl 3):89-94.

Needleman HL, Reiss JA, Tobin MJ, Biesecher G, Greenhouse J. 1996. Bone lead levels and delinquent behavior. JAMA 275:363-369.

Needleman, NL, C McFarland, RB Ness, SE Fienberg and MJ Tobin. 2002. Bone lead levels in adjudicated delinquents. A case control study. Neurotoxicology and Teratology 24:711-717.

Nulman I, O'Haydon B, Gladstone J, Koren G. 1998. The effects of alcohol in the fetal brain. In: Handbook of Developmental Neurotoxicology (Slikker W, Chang LW, eds). San Diego, CA:Academic Press.

Opler, MGA, AS Brown, J Graziano, M Desai, W Zheng, C Schaefer, P Factor-Litvak and ES Susser. 2004. Prenatal lead exposure, δ-Aminolevulinic acid and schizophrenia. Environmental Health Perspectives doi:10.1289/ehp.6777 (available at http://dx.doi.org/).

Oscar, K and T Hawkins. 1977. Microwave alteration of the blood-brain barrier system of rats. Brain Research 126:281-293

Osius N, Karmaus W, Kruse H, Witten J.1999. Exposure to polychlorinated biphenyls and levels of thyroid hormones in children. Environmental Health Perspectives 107:843-849.

Parrill M. 1996. Research implications for health and human services. In: Learning Disabilities, Lifelong Issues (Cramer S, Ellis W, eds). Baltimore, MD: Paul W. Brookes Publishing.

Patandin S, Lanting CI, Mulder PG, Boersma E, Sauer P, Weisglas-Kuperus N. 1999. Effects of environmental exposure to polychlorinated biphenyls and dioxins on cognitive abilities in Dutch children at 42 months of age. J Pediatr 134(1):33-41.

Pearson M, Hoyme H, Seaver L, Rimsza M. 1994. Toluene embryopathy: delineation of the phenotype and comparison with fetal alcohol syndrome. Pediatrics 93(2):211-215.

Perera, F, V Rauh, WY Tsai, P Kinney, D Camann, D Barr, T Bernert, R Garfinkel, Y-H Tu, D Diaz, J Dietrich and RM Whyatt. 2003. Effects of transplacental exposure to environmental pollutants on birth outcomes in a multi-ethnic population. Environmental Health Perspectives 111:201-205.

Pihl RO, Parkes M. 1977. Hair element content in learning disabled children. Science 198:204-206 (1977).

Plomin R, Owen M, McGuffin P. The genetic basis of complex human behaviors. Science 264:1733-1739.

Rice D, Evangelista de Duffard A, Duffard R, Iregren A, Satoh H, Watanabe C. 1996. Lessons for neurotoxicology from selected model compounds: SGOMSEC joint report. Environmental Health Perspectives 104(suppl 2):205-215.

Rice DC, Hayward S. 1997. Effects of postnatal exposure to a PCB mixture in monkeys on nonspatial discrimination reversal and delayed alternation performance. NeuroToxicology 18(2):479-494.

Rice, DC. 1997. Effects of postnatal exposure to a PCB mixture in monkeys on multiple fixed interval-fixed ratio performance. Neurotoxicology and Teratology 19:1-6.

Rice DC. 1998. Developmental lead exposure: neurobehavioral consequences. In: Handbook of Developmental Neurotoxicology (Slikker W, Chang LW, eds). San Diego, CA: Academic Press.

Rice, DC. 1998. Effects of postnatal exposure of monkeys to a PCB mixture on spatial discrimination reversal and DRL performance. Neurotoxicology and Teratology 20(4):391-400.

Rice DC. 1999. Behavioral impairment produced by low-level postnatal PCB exposure in monkeys. Environ Res (sect A) 80:S113-121.

Rosenman K, Guss P. 1997. Prevalence of congenital deficiency in serum cholinesterase. Arch Environ Health 52(1):42-44.

Sager PR. 1988. Selectivity of methylmercury effects on cytoskeleton and mitotic progression in cultured cells. Toxicol Appl Pharm 94(3):473-486.

Sager PR, Matheson DW. 1988. Mechanisms of neurotoxicity related to selective disruption of microtubules and intermediate filaments. Toxicology 49(2-3):479-492.

Salford, LG, AE Brun, JL Eberhadrt, L Malmgren and BPR Persson. 2003. Nerve cell damage in mammalian brain after exposures to microwaves from GSM mobile phones. Environmental Health Perspectives 111:881-883.

Schettler T, Stein J, Reich F, Valenti M.2000. In Harm's Way: Toxic Threats to Child Development. Boston: Greater Boston Physicians for Social Responsibility. Available: http://www.igc.org/psr and all primary references cited therein (cited 26 October 2001).

Schober, SE, TH Sinks, RL Jones, PM Bolger, M McDowell, J Osterloh, ES Garrett, RA Canady, CF Dillon, Y Sun, CB Joseph and KR Mahaffey. 2003. Blood mercury levels in US children and women of childbearing age, 1999-2000. Journal of the American Medical Association 289:1667-1674.

Shigeta S, Miyake K, Aikawa H, Misawa T. 1989. Effects of postnatal low-levels of exposure to styrene on behavior and development in rats. J Toxicol Sci 14(4):279-286.

She J, Petreas M, Winkler J, Visita P, McKinney M, Kopec D. 2002. PBDEs in the San Francisco Bay Area: measurements in harbor seal blubber and human breast adipose tissue. Chemosphere 46:697-707.

Stewart P, Reihman J, Lonky E, Darvill T, Pagano J. 2000. Prenatal PCB exposure and neonatal behavioral assessment scale (NBAS) performance. Neurotoxicol Teratol 22(1):21-29.

Taylor DH, Lagory KE, Zaccaro DJ, et al. 1985. Effect of trichloroethylene on the exploratory and locomotor activity of rats exposed during development. Sci Total Environ 47:415-420.

Tilson HA. 1997. Neurochemical effects of PCBs--an overview. NeuroToxicology 18(3):727-744.

U.S. Department of Health and Human Services. 1999. Attention-Deficit/Hyperactivity Disorder. Chapter 3 in Mental Health: A Report of the Surgeon General. Rockville, MD.

U.S. EPA. 1997. Mercury Study Report to Congress. EPA-452/R-97-003. Washington, DC: U.S. Environmental Protection Agency.

Volarcik, K, L Sheean, J Goldfarb, L Woods, FW Abdul-Karim and P Hunt. 1998. The meiotic competence of in-vitro matured human oocytes is influenced by donor age: evidence that folliculogenesis is compromised in the reproductively aged ovary. Human Reproduction 13:154-160.

Vreugdenhil, HJI, FME Slijper, PGH Mulder, and N Weisglas-Kuperus 2002. Effects of perinatal exposure to PCBs and dioxins on play behavior in Dutch children at school age. Environmental Health Perspectives 110:A593-A598.

Whyatt RM, Barr DB. 2001. Measurement of organophosphate metabolites in postpartum meconium as a potential biomarker of prenatal exposure: a validation study. Environmental Health Perspectives 109(4):417-20.

Zhou T, DG Ross, MJ DeVito, and KM Crofton. 2001. Effects of short-term in vivo exposure to polybrominated diphenyl ethers on thyroid hormones and hepatic enzyme activities in weanling rats. Toxicological Sciences 61:76-82.

Zhou T, MM Taylor, MJ DeVito, and KM Crofton. 2002. Developmental exposure to brominated diphenyl ethers results in thyroid hormone disruption. Toxicolological Sciences 66:105- 116.

Zoeller RT, Dowling A, Vas A. 2000. Developmental exposure to polychlorinated biphenyls exerts thyroid hormone-like effects on the expression of RC3/neurogranin and myelin basic protein messenger ribonucleic acids in the developing rat brain. Endocrinology 141(1):181-189.