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Fertility/Reproductive Health
Working Group

CHE's Fertility & Reproductive Health Working Group convenes over 450 diverse members around environmental impacts on fertility and reproductive health. The goal of this dynamic conversation is to discern what the science is telling us, where the research gaps are, and how we can effectively support and promote science-based education and action. Read more...

If you would like to join and are already a CHE Partner, send us an email request. Or become a CHE Partner and indicate your interest in your application.

For more information, please contact Karin Russ at karin@healthandenvironment.org.

WHAT'S NEW

Highlights, September 2014

PPTOXIV: Environmental Stressors in Disease and Implications for Human Health
October 26–29, 2014. Boston, MA. The Endocrine Society is sponsoring the fourth international summit of Prenatal Programming and Toxicity (PPTOX) – a conference series dedicated to cutting-edge discussion of environmental hazards during early life and long-term consequences. PPTOX is one of the premier international venues for scientists to evaluate current knowledge and guide forward momentum for this burgeoning field. Advanced registration rates end September 10th.

Superfund Research Program (SRP) Annual Meeting
November 12–14, 2014, San Jose, CA. The SRP annual meeting will bring together researchers, trainees, and administrators supported by the program, representatives from partner agencies, including the U.S. Environmental Protection Agency (USEPA) and the Agency for Toxic Substances and Disease Registry (ATSDR). National Institute of Environmental Health Sciences (NIEHS).

APHA 2014 Annual Meeting & Exposition
November 15–19, 2014, New Orleans, LA. The meeting will address current and emerging health science, policy, and practice issues in an effort to prevent disease and promote health.  American Public Health Association (APHA).

Children's Environmental Health Network 2015 Research Conference
February 4–6, 2015, Austin, TX. This conference will explore how the interaction between food and environmental factors affect children's health. Children's Environmental Health Network (CEHN).

Reproductive Environmental Health Articles-Endometriosis and PCOS

A population-based case-control study of urinary bisphenol A concentrations and risk of endometriosis
Our study suggests that increased urinary BPA is associated with an increased risk of non-ovarian pelvic endometriosis, but not ovarian endometriosis. The significant associations observed in this study suggest that BPA may affect the normal dynamic structural changes of hormonally responsive endometrial tissue during the menstrual cycle, promoting the establishment and persistence of refluxed endometrial tissue in cases with non-ovarian pelvic endometriosis. Human Reproduction.

Risk for estrogen-dependent diseases in relation to phthalate exposure and polymorphisms of CYP17A1 and estrogen receptor genes
We recruited 44 patients with endometriosis or adenomyosis, 36 patients with leiomyoma, and 69 healthy controls from a medical center in Taiwan between 2005 and 2007. Our results suggested that both CYP17A1 and ESR1 polymorphisms may modulate the effects of phthalate exposure on the development of leiomyoma. Environmental Science and Pollution Research International.

Bisphenol A and the female reproductive tract: an overview of recent laboratory evidence and epidemiological studies
The aim of this review is to summarize the recent experimental studies describing the effects and mechanisms of BPA on the female genital tract and to compare them to the current knowledge regarding the impact of BPA impact on female reproductive health. In particular, BPA has been correlated with alterations in hypothalamic-pituitary hormonal production, reduced oocyte quality due to perinatal and adulthood exposure, defective uterine receptivity and the pathogenesis of polycystic ovary syndrome. Researchers have reported conflicting results regarding the effect of BPA on premature puberty and endometriosis development. Reproductive Biology & Endocrinology.

Soy but not Bisphenol A (BPA) Induces Hallmarks of Polycystic Ovary Syndrome (PCOS) and Related Metabolic co-Morbidities in Rats
Developmental exposure to endocrine disrupting compounds (EDCs) have been hypothesized to exacerbate risk, in part because PCOS hallmarks and associated metabolic co-morbidities can be reliably induced in animal models by perinatal androgen exposure. Here we show that lifetime exposure to a soy diet, containing endocrine active phytoestrogens, but not developmental exposure (gestational day 6-lactational day 40) to the endocrine disrupting monomer Bisphenol A (BPA), can induce key features of PCOS in the rat. Reproductive Toxicology.

See a searchable calendar with events of interest to this working group.

UCSF Program on Reproductive Health and the Environment present Visionary Leadership Awards

6/14/13: The UCSF PRHE program awarded its Visionary Leadership Award at the start of The Endocrine Society Meeting in San Francisco to three prominent leaders of professional societies. Teresa Woodruff, President-elect of The Endocrine Society, Linda Giudice, President of the American Society for Reproductive Medicine, and Jeanne Conry, President of the American Congress of Obstetricians and Gynecologists were this year's recipients. The award is given to visionary leaders working to improve reproductive health by preventing harmful environmental exposures.

Pictured above (L-R) are PRHE Director, Tracey Woodruff with Linda Giudice and CHE Fertility founder, Alison Carlson. Below, Vice-Chair of CHE Michael Lerner, Alison Carlson, former CHE Fertility coordinator Julia Varshavsky, and current coordinator Karin Russ gather to commemorate the occasion.

Second Annual CHE/NIEHS Women's Environmental Reproductive Health Consortium Meeting

For additional information, visit: Women's Environmental Reproductive Health Consortium. 
 

 

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