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Fertility/Reproductive Health
Working Group

CHE's Fertility & Reproductive Health Working Group convenes over 450 diverse members around environmental impacts on fertility and reproductive health. The goal of this dynamic conversation is to discern what the science is telling us, where the research gaps are, and how we can effectively support and promote science-based education and action. Read more...

If you would like to join and are already a CHE Partner, send us an email request. Or become a CHE Partner and indicate your interest in your application.

For more information, please contact Karin Russ at karin@healthandenvironment.org.


Highlights, December 2014

CEHN Research Conference- Children: Food and Environment
Children's Environmental Health Network; February 4-6, 2015; Austin, Texas. This exciting conference will highlight cutting edge science and offer the translation of findings to public health practice and policy. The conference program will organize around specified health and developmental outcomes or affected organ/body systems, and include presentations on micro-level influences such as nutrient mediated microbiome effects as well as macro-level influences such as contaminants rising from modern food production practices. Co-sponsored by Environmental Health Perspectives and the International Society for Children’s Health and the Environment.

Reproductive Environmental Health articles: Fetal Programming


Transgenerational effects of binge drinking in a primate model: implications for human health
This study examines whether binge ethanol consumption before ovulation affects oocyte quality, gene expression, and subsequent embryodevelopment in female rhesus monkeys. The authors provide evidence that binge drinking can affect the developmental potential of oocytes even after alcohol consumption has ceased. Fertility and Sterility.

Genetic and epigenetic catalysts in early-life programming of adult cardiometabolic disorders
Evidence has emerged across the past few decades that the lifetime risk of developing morbidities like type 2 diabetes, obesity, and cardiovascular disease may be influenced by exposures that occur in utero and in childhood. This review provides an overview of these concepts. Diabetes, Metabolic Syndrome, Obesity: targets and therapy.

DNA methylation alterations in response to prenatal exposure of maternal cigarette smoking: A persistent epigenetic impact on health from maternal lifestyle?
It has been proposed that epigenetic mechanisms constitute the link between prenatal exposure to maternal cigarette smoking and the diverse pathologies arising in later life. This review examines the current literature, focusing on DNA methylation. Archives of Toxicology.

Inhalation of fine particulate matter during pregnancy increased IL-4 cytokine levels in the fetal portion of the placenta
This study aimed to verify the development of placental and systemic inflammation in rats exposed to fine particulate matter before or during pregnancy. Increased IL-4 suggests that a placental inflammatory reaction may have occurred in response to exposure to fine particulate matter and that this cytokine was responsible, among possibly others factors, for resolution of the inflammatory reaction. Toxicology Letters.

Stress-induced Perinatal and Transgenerational Epigenetic Programming of Brain Development and Mental Health
Research efforts during the past decades have provided intriguing evidence suggesting that stressful experiences during pregnancy exert long-term consequences on the future mental wellbeing of both the mother and her baby. Based on existing evidence, we propose that prenatal stress, through the generation of epigenetic alterations, becomes one of the most powerful influences on mental health in later life. Neuroscience and Behavioral Reviews.

See a searchable calendar with events of interest to this working group.

UCSF Program on Reproductive Health and the Environment present Visionary Leadership Awards

6/14/13: The UCSF PRHE program awarded its Visionary Leadership Award at the start of The Endocrine Society Meeting in San Francisco to three prominent leaders of professional societies. Teresa Woodruff, President-elect of The Endocrine Society, Linda Giudice, President of the American Society for Reproductive Medicine, and Jeanne Conry, President of the American Congress of Obstetricians and Gynecologists were this year's recipients. The award is given to visionary leaders working to improve reproductive health by preventing harmful environmental exposures.

Pictured above (L-R) are PRHE Director, Tracey Woodruff with Linda Giudice and CHE Fertility founder, Alison Carlson. Below, Vice-Chair of CHE Michael Lerner, Alison Carlson, former CHE Fertility coordinator Julia Varshavsky, and current coordinator Karin Russ gather to commemorate the occasion.

Second Annual CHE/NIEHS Women's Environmental Reproductive Health Consortium Meeting

For additional information, visit: Women's Environmental Reproductive Health Consortium. 


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